rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1994-8-2
|
pubmed:abstractText |
We evaluated the usefulness of a recombinant parasite antigen (recSXP1) for the serologic diagnosis of lymphatic filariasis. A large proportion of sera from microfilaremic donors living in five different endemic countries (356 of 446 [80%]) contained IgG antibodies to recSXP1, as do sera from approximately 33% of amicrofilaremic patients with acute filarial disease and/or indirect evidence of active filarial infection. Exposure to filarial worms per se does not appear sufficient to elicit an anti-SXP1 antibody response. Thus, this serologic test identifies a large proportion of persons with active lymphatic filariasis among residents of endemic areas.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0002-9637
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
727-34
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:8024066-Animals,
pubmed-meshheading:8024066-Antibodies, Helminth,
pubmed-meshheading:8024066-Antigens, Helminth,
pubmed-meshheading:8024066-Brugia malayi,
pubmed-meshheading:8024066-Elephantiasis, Filarial,
pubmed-meshheading:8024066-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8024066-Humans,
pubmed-meshheading:8024066-Immune Sera,
pubmed-meshheading:8024066-Immunoglobulin G,
pubmed-meshheading:8024066-Microfilaria,
pubmed-meshheading:8024066-Recombinant Proteins,
pubmed-meshheading:8024066-Wuchereria bancrofti
|
pubmed:year |
1994
|
pubmed:articleTitle |
Evaluation of a recombinant parasite antigen for the diagnosis of lymphatic filariasis.
|
pubmed:affiliation |
Department of Tropical Public Health, Harvard School of Public Health, Boston, Massachusetts.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|