Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1978-10-27
|
| pubmed:abstractText |
The urinary excretion of albumin and beta 2-microglobulin in a population of 294 persons, living in an area where Balkan nephropathy is endemic, has been studied. In fifty-six (about 19%) of the subjects the beta 2-microglobulin concentration was above the +2 SD level for a reference group of healthy individuals from non-endemic areas. Albumin elevation was found in forty-four (about 15%) of the cases. In twenty-one of the subjects the urinary concentration of both beta 2-microglobulin and albumin were increased, in sixteen of these cases the relationship between the two proteins was consistent with tubular proteinuria. An increased beta 2-microglobulin excretion is considered to be a sign of Balkan nephropathy. Radioimmunoassay of the protein is sensitive enough to detect tubular proteinuria at an early stage and is suggested as a suitable screening test for the disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0036-5513
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
169-73
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:80021-Adolescent,
pubmed-meshheading:80021-Adult,
pubmed-meshheading:80021-Aged,
pubmed-meshheading:80021-Albuminuria,
pubmed-meshheading:80021-Beta-Globulins,
pubmed-meshheading:80021-Child,
pubmed-meshheading:80021-Child, Preschool,
pubmed-meshheading:80021-Female,
pubmed-meshheading:80021-Humans,
pubmed-meshheading:80021-Infant,
pubmed-meshheading:80021-Infant, Newborn,
pubmed-meshheading:80021-Male,
pubmed-meshheading:80021-Mass Screening,
pubmed-meshheading:80021-Middle Aged,
pubmed-meshheading:80021-Nephritis, Interstitial,
pubmed-meshheading:80021-Radioimmunoassay,
pubmed-meshheading:80021-Romania,
pubmed-meshheading:80021-beta 2-Microglobulin
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Urinary excretion of albumin and beta 2-microglobulin in a population from an area where Balkan nephropathy is endemic.
|
| pubmed:publicationType |
Journal Article
|