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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011777,
umls-concept:C0025853,
umls-concept:C0034656,
umls-concept:C0042963,
umls-concept:C0061863,
umls-concept:C0205195,
umls-concept:C0442027,
umls-concept:C1257890,
umls-concept:C1707455,
umls-concept:C1708528,
umls-concept:C2603343
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|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1995-1-13
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|
pubmed:abstractText |
Three anti-emetic treatment regimens were compared in 357 patients receiving cisplatin therapy (mean dose 81 mg/m2) in this double-blind randomized study. Regimens studied were i) granisetron 1 mg bd orally for 7 days (granisetron alone); ii) gran 1 mg bd orally for 7 days plus prophylactic dexamethasone (12 mg i.v.) on the first day only (gran/dex); iii) metoclopramide (3 mg/kg i.v. loading dose; 4 mg/kg i.v. infusion) plus dex (12 mg i.v.) on the first day followed by met 10 mg orally tds for a further 6 days (met/dex).
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0923-7534
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7993831-Administration, Oral,
pubmed-meshheading:7993831-Adult,
pubmed-meshheading:7993831-Aged,
pubmed-meshheading:7993831-Chi-Square Distribution,
pubmed-meshheading:7993831-Cisplatin,
pubmed-meshheading:7993831-Constipation,
pubmed-meshheading:7993831-Dexamethasone,
pubmed-meshheading:7993831-Double-Blind Method,
pubmed-meshheading:7993831-Drug Therapy, Combination,
pubmed-meshheading:7993831-Europe,
pubmed-meshheading:7993831-Female,
pubmed-meshheading:7993831-Granisetron,
pubmed-meshheading:7993831-Headache,
pubmed-meshheading:7993831-Humans,
pubmed-meshheading:7993831-Male,
pubmed-meshheading:7993831-Metoclopramide,
pubmed-meshheading:7993831-Middle Aged,
pubmed-meshheading:7993831-Nausea,
pubmed-meshheading:7993831-Prognosis,
pubmed-meshheading:7993831-South Africa,
pubmed-meshheading:7993831-Vomiting
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pubmed:year |
1994
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pubmed:articleTitle |
Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group.
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pubmed:affiliation |
Centre François Baclesse, Caen, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study
|
