| pubmed-article:7979498 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7979498 | lifeskim:mentions | umls-concept:C0042373 | lld:lifeskim |
| pubmed-article:7979498 | lifeskim:mentions | umls-concept:C0241889 | lld:lifeskim |
| pubmed-article:7979498 | lifeskim:mentions | umls-concept:C0201950 | lld:lifeskim |
| pubmed-article:7979498 | lifeskim:mentions | umls-concept:C1548835 | lld:lifeskim |
| pubmed-article:7979498 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7979498 | pubmed:dateCreated | 1994-12-23 | lld:pubmed |
| pubmed-article:7979498 | pubmed:abstractText | Hypercholesterolaemia is a major risk factor for the development of coronary heart disease (CHD). Early detection and management of hypercholesterolaemia could retard the atherosclerotic process. Given that CHD and hypercholesterolaemia cluster within families, a screening strategy based on a family history of vascular disease has been advocated. Serum total cholesterol concentrations were measured in a random stratified sample of 1012 children aged from 12-15 years old participating in a coronary risk factor surveillance study in Northern Ireland. Information about vascular disease in close family members was obtained by means of a questionnaire. The study population was divided into two groups according to total cholesterol values: (i) normal, < 5.2 mmol/l (n = 822) and (ii) raised, > or = 5.2 mmol/l (n = 190). A family history identified 63 out of 190 individuals with hypercholesterolaemia yielding a sensitivity of 33.2% and specificity of 71.5%. Our data indicated that a strategy whereby only children from high risk families are screened for hypercholesterolaemia is ineffective. While primary prevention emphasising a healthy diet for all is essential, the role of universal screening deserves further appraisal. | lld:pubmed |
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| pubmed-article:7979498 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7979498 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7979498 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7979498 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7979498 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7979498 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7979498 | pubmed:issn | 1468-2044 | lld:pubmed |
| pubmed-article:7979498 | pubmed:author | pubmed-author:ChaoM DMD | lld:pubmed |
| pubmed-article:7979498 | pubmed:author | pubmed-author:SavageJ MJM | lld:pubmed |
| pubmed-article:7979498 | pubmed:author | pubmed-author:StrainJ JJJ | lld:pubmed |
| pubmed-article:7979498 | pubmed:author | pubmed-author:BorehamC ACA | lld:pubmed |
| pubmed-article:7979498 | pubmed:author | pubmed-author:PrimroseE DED | lld:pubmed |
| pubmed-article:7979498 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:7979498 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:7979498 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7979498 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7979498 | pubmed:pagination | 239-42 | lld:pubmed |
| pubmed-article:7979498 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:7979498 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7979498 | pubmed:articleTitle | Cholesterol screening and family history of vascular disease. | lld:pubmed |
| pubmed-article:7979498 | pubmed:affiliation | Department of Child Health, Institute of Clinical Science, Royal Victoria Hospital, Belfast. | lld:pubmed |
| pubmed-article:7979498 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7979498 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7979498 | lld:pubmed |
