pubmed-article:7970088 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7970088 | lifeskim:mentions | umls-concept:C0403416 | lld:lifeskim |
pubmed-article:7970088 | lifeskim:mentions | umls-concept:C0332240 | lld:lifeskim |
pubmed-article:7970088 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:7970088 | pubmed:dateCreated | 1994-11-29 | lld:pubmed |
pubmed-article:7970088 | pubmed:abstractText | Crescentic glomerulonephritis is usually classified into antiglomerular basement membrane (GBM) disease, immune-complex disease, or pauci-immune crescentic nephritis. The last category includes patients with systemic vasculitis as well as 'idiopathic' isolated crescentic nephritis. The presence of anti-neutrophil cytoplasmic antibodies (ANCA) in many patients with apparently isolated crescentic nephritis suggests that this represents a renal-limited form of vasculitis, and that truly 'idiopathic' crescentic nephritis is a very rare entity. We reviewed all renal biopsies with extracapillary proliferation seen at our centre since the availability of an ANCA assay (4-year period). There were 89 such biopsies of a total of 1240, of which 82 had sufficient details for further analysis. Of these, 10 had anti-GBM disease, 35 had epithelial proliferation associated with a variety of other diseases, and 36 had ANCA-associated disease. Nine of this last group had no extrarenal features and would previously have been classified as 'idiopathic' crescentic glomerulonephritis. The single remaining patient had an inactive glomerulonephritis with a scarred crescent; the predominant lesion was an interstitial nephritis. We therefore conclude that truly 'idiopathic' crescentic nephritis is very rare, if it exists at all. The ability to provide a practically complete classification of crescentic nephritis has important prognostic and therapeutic consequences. | lld:pubmed |
pubmed-article:7970088 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7970088 | pubmed:language | eng | lld:pubmed |
pubmed-article:7970088 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7970088 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:7970088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7970088 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7970088 | pubmed:issn | 0931-0509 | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:LockwoodC MCM | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:ThiruSS | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:OliveiraD BDB | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:EsnaultV LVL | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:ShortA KAK | lld:pubmed |
pubmed-article:7970088 | pubmed:author | pubmed-author:AngangcoRR | lld:pubmed |
pubmed-article:7970088 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7970088 | pubmed:volume | 9 | lld:pubmed |
pubmed-article:7970088 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7970088 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7970088 | pubmed:pagination | 630-6 | lld:pubmed |
pubmed-article:7970088 | pubmed:dateRevised | 2010-8-25 | lld:pubmed |
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pubmed-article:7970088 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7970088 | pubmed:articleTitle | Does truly 'idiopathic' crescentic glomerulonephritis exist? | lld:pubmed |
pubmed-article:7970088 | pubmed:affiliation | Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, UK. | lld:pubmed |
pubmed-article:7970088 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7970088 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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