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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1994-12-20
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pubmed:abstractText |
A 55-year-old man was admitted to our department because of shortness of breath and pancytopenia on March 27, 1992. On admission, palpebral conjuctiva were anemic. Laboratory findings showed pancytopenia, a reticulocyte count of 44,835/microliters, hemosiderinuria, LDH of 710 IU/l, haptoglobin of 6 mg/dl, NAP score of 301, red cell acetylcholinesterase of 1.5 U, negative Ham's test and negative sugar water test. Bone marrow was hypoplastic (2.4 x 10(4)/microliters). The erythrocytes of this patient showed complement-sensitive cells by the complement lysis sensitivity test, and a negative population consisting of double negative erythrocytes by flow cytometric two-color analysis using monoclonal antibodies to CD55 and CD59. A diagnosis of PNH with hypoplastic bone marrow was thus made. Therefore, flow cytometric two-color analysis appears to be superior to the standard tests currently used.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0485-1439
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
898-901
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7967061-Antibodies, Monoclonal,
pubmed-meshheading:7967061-Antigens, CD,
pubmed-meshheading:7967061-Flow Cytometry,
pubmed-meshheading:7967061-Hemoglobinuria, Paroxysmal,
pubmed-meshheading:7967061-Hemolysis,
pubmed-meshheading:7967061-Humans,
pubmed-meshheading:7967061-Male,
pubmed-meshheading:7967061-Middle Aged
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pubmed:year |
1994
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pubmed:articleTitle |
[Negative Ham's test and sugar water test on admission in paroxysmal nocturnal hemoglobinuria].
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pubmed:affiliation |
First Department of Internal Medicine, Fukushima Medical College.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|