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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1994-11-28
pubmed:abstractText
A pulse-wave Doppler ultrasound was used to identify fetal umbilical cord and to obtain flow-velocity waveforms. The umbilical artery Doppler indices were determined in 34 fetuses with major congenital malformations between 20 and 38 wks' gestation. Reference ranges of fetal umbilical artery systolic and diastolic (S/D) ratio, pulsatility index (PI) and resistance index (RI) with gestation were constructed from a cross-sectional study of 331 appropriate for gestation age fetuses of 16 to 41 wks' gestation. The records were reviewed to determine the changes associated with fetal malformation. Twenty five of 34 patients with major congenital anomalies showed high S/D ratio, PI and RI in waveforms taken from the umbilical artery. All fetuses with chromosomal aneuploidy (10 cases) had high umbilical artery S/D ratio, PI and RI. It appears that a fetal mechanism may determine the changes in the umbilical placental circulation resulting in an umbilical artery pattern of high flow resistance in fetuses with congenital anomalies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0125-2208
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-500
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Doppler umbilical artery flow velocity waveforms in pregnancies complicated by major fetal malformations.
pubmed:affiliation
Department of Obstetrics & Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
pubmed:publicationType
Journal Article