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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1994-12-2
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pubmed:abstractText |
The chromosomal location of SCN5A, the gene encoding the principal voltage-gated Na+ channel expressed in human heart, has been determined by three independent methodologies: somatic cell hybrid mapping, chromosomal microdissection-polymerase chain reaction, and fluorescence in situ hybridization. The SCN5A gene was assigned to the short arm of chromosome 3 (band 3p21) by all three approaches. These data are further evidence that striated muscle Na+ channel genes are dispersed in the genome.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-0171
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:geneSymbol |
SCN5A
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7956363-Animals,
pubmed-meshheading:7956363-Base Sequence,
pubmed-meshheading:7956363-Chromosome Banding,
pubmed-meshheading:7956363-Chromosome Mapping,
pubmed-meshheading:7956363-Chromosomes, Human, Pair 3,
pubmed-meshheading:7956363-DNA Primers,
pubmed-meshheading:7956363-Drug Resistance,
pubmed-meshheading:7956363-Hominidae,
pubmed-meshheading:7956363-Humans,
pubmed-meshheading:7956363-Hybrid Cells,
pubmed-meshheading:7956363-In Situ Hybridization, Fluorescence,
pubmed-meshheading:7956363-Molecular Sequence Data,
pubmed-meshheading:7956363-Myocardium,
pubmed-meshheading:7956363-Polymerase Chain Reaction,
pubmed-meshheading:7956363-Rodentia,
pubmed-meshheading:7956363-Sodium Channels,
pubmed-meshheading:7956363-Tetrodotoxin
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pubmed:year |
1995
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pubmed:articleTitle |
Assignment of the human heart tetrodotoxin-resistant voltage-gated Na+ channel alpha-subunit gene (SCN5A) to band 3p21.
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pubmed:affiliation |
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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