Linked Life Data

7931944

Source:http://linkedlifedata.com/resource/pubmed/id/7931944

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-11-23
pubmed:abstractText
This work deals with the preparation of corticosteroid-loaded albumin microspheres designed for intra-articular administration. Dexamethasone was chosen as the model drug and bovine serum albumin was used as the biodegradable, natural polymer. Albumin microspheres were produced by spray drying, a 'one-step' technique seldom used in the preparation of microparticulate drug delivery systems with particle sizes < 10 microns. The effects of both polymer/drug ratio used in the formulations and the different heat-stabilization conditions were evaluated on morphology, size, solubility characteristics, drug loading and 'in vitro' drug release of the microparticles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0265-2048
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
445-54
pubmed:dateRevised
2009-7-21
pubmed:meshHeading
pubmed:articleTitle
Spray-dried albumin microspheres for the intra-articular delivery of dexamethasone.
pubmed:affiliation
Dipartimento di Chimica Farmaceutica, Università di Pavia, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't