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pubmed-article:7919504pubmed:dateCreated1994-11-16lld:pubmed
pubmed-article:7919504pubmed:abstractTextThe search for alternatives to carbon dioxide (CO2) for insufflation during laparoscopy has included the consideration of helium. Helium is attractive because it is noncombustible and has no pharmacologic effects. Unfortunately, it is also relatively insoluble in blood, which potentially could exacerbate a venous gas embolism. We performed rapid intravenous injections of CO2 and helium into 4 dogs in amounts ranging from 5 to 10 ml of gas per kilogram body weight. Recovery after CO2 injection always occurred within 1 min. In 4 of 6 instances, the helium injection was fatal. Our results confirm that helium is more lethal than CO2 when injected intravenously. This implies that the use of helium for insufflation during laparoscopy might place patients at greater risk for adverse effects should venous gas embolism occur.lld:pubmed
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pubmed-article:7919504pubmed:authorpubmed-author:WolfJ SJSJrlld:pubmed
pubmed-article:7919504pubmed:authorpubmed-author:StollerM LMLlld:pubmed
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pubmed-article:7919504pubmed:pagination173-7lld:pubmed
pubmed-article:7919504pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:7919504pubmed:year1994lld:pubmed
pubmed-article:7919504pubmed:articleTitleGas embolism: helium is more lethal than carbon dioxide.lld:pubmed
pubmed-article:7919504pubmed:affiliationDepartment of Urology, University of California School of Medicine, San Francisco.lld:pubmed
pubmed-article:7919504pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7919504pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:7919504pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed