Linked Life Data

7919504

Source:http://linkedlifedata.com/resource/pubmed/id/7919504

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-11-16
pubmed:abstractText
The search for alternatives to carbon dioxide (CO2) for insufflation during laparoscopy has included the consideration of helium. Helium is attractive because it is noncombustible and has no pharmacologic effects. Unfortunately, it is also relatively insoluble in blood, which potentially could exacerbate a venous gas embolism. We performed rapid intravenous injections of CO2 and helium into 4 dogs in amounts ranging from 5 to 10 ml of gas per kilogram body weight. Recovery after CO2 injection always occurred within 1 min. In 4 of 6 instances, the helium injection was fatal. Our results confirm that helium is more lethal than CO2 when injected intravenously. This implies that the use of helium for insufflation during laparoscopy might place patients at greater risk for adverse effects should venous gas embolism occur.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1052-3901
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Gas embolism: helium is more lethal than carbon dioxide.
pubmed:affiliation
Department of Urology, University of California School of Medicine, San Francisco.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't