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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1994-11-10
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pubmed:abstractText |
Trends in one-year graft survival rates seen in the past 30 years were examined in the UCLA and UNOS Registries. Some of the trends noted were as follows: 1. One-year graft survival rates for cadaver-donor transplants improved from 40% to 80% during this 30-year period. One-year patient survival improved from 50% to 95%. Transplants from living-related donors improved in graft survival from 80% to 90-95%. 2. Factors that diminished in importance were: recipient race, sensitization, primary disease, HLA haplotype matching in living donors, recipient and donor sex, kidney sharing, and transfusions. 3. Factors that continue to provide about a 10% variation of one-year graft survival are: cold ischemia time, HLA mismatch, recipient and donor age. 4. Posttransplantation, factors such as first-day diuresis, one-week dialysis, rejection at discharge, and discharge serum creatinine continue to be very important determinants of future outcome in 6 yearly subsets of patients. 5. Induction by ALG and OKT3 was shown in 6 subsets to have no effect on one-year graft survival. 6. Future trend studies will be needed to examine the 5-year long-term effects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0890-9016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
553-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7918188-Adolescent,
pubmed-meshheading:7918188-Adult,
pubmed-meshheading:7918188-Age Factors,
pubmed-meshheading:7918188-Aged,
pubmed-meshheading:7918188-Child,
pubmed-meshheading:7918188-Female,
pubmed-meshheading:7918188-Graft Survival,
pubmed-meshheading:7918188-Histocompatibility Testing,
pubmed-meshheading:7918188-Humans,
pubmed-meshheading:7918188-Ischemia,
pubmed-meshheading:7918188-Kidney,
pubmed-meshheading:7918188-Kidney Transplantation,
pubmed-meshheading:7918188-Male,
pubmed-meshheading:7918188-Middle Aged,
pubmed-meshheading:7918188-Organ Preservation,
pubmed-meshheading:7918188-Tissue Donors
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pubmed:year |
1993
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pubmed:articleTitle |
Thirty-year trends in clinical kidney transplantation.
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pubmed:publicationType |
Journal Article
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