Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-1-25
pubmed:abstractText
In an attempt to correlate the presence of subepidermal and renal glomerular deposits in murine lupus, skin and kidney tissue from 67 (NZB X W)F1 mice was examined by direct immunofluorescence and the results tabulated. Between 36 and 43 weeks of age, deposits in both locations were detected in only 50.5% of the mice, and between 44 and 52 weeks, in only 79.0%. The titer of antibody to DNA did not correlate with the presence of subepidermal deposits even though DNA was demonstrated at the epidermal-dermal interface. It is concluded that the absence of immunoglobulin in the subepidermis does not preclude the presence of renal deposits, and it is hazardous to attempt to predict underlying glomerular deposition by performing immunofluorescence examination of skin in murine lupus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0011-9075
pubmed:author
pubmed:issnType
Print
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-13
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Relationship of subepidermal immune complex to renal deposits in the (NZB X W)F1 mouse.
pubmed:publicationType
Journal Article