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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-7-18
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pubmed:abstractText |
Cladribine (2-CdA, 2-chlorodeoxyadenosine), a chlorinated adenosine analog, is active in the treatment of hairy cell leukemia and other hematologic malignancies, but its use in treating solid tumors is still under investigation, as is the optimal schedule for administering this drug. The authors conducted a dose-finding study to define the maximal tolerated dose and toxicities of this agent when given to patients with refractory solid tumors having normal renal, hepatic, and bone marrow function.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
168-73
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:7911736-Adult,
pubmed-meshheading:7911736-Aged,
pubmed-meshheading:7911736-Blindness,
pubmed-meshheading:7911736-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:7911736-Cladribine,
pubmed-meshheading:7911736-Colorectal Neoplasms,
pubmed-meshheading:7911736-Drug Administration Schedule,
pubmed-meshheading:7911736-Female,
pubmed-meshheading:7911736-Humans,
pubmed-meshheading:7911736-Lung Neoplasms,
pubmed-meshheading:7911736-Male,
pubmed-meshheading:7911736-Middle Aged,
pubmed-meshheading:7911736-Neoplasms,
pubmed-meshheading:7911736-Neutropenia,
pubmed-meshheading:7911736-Thrombocytopenia
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pubmed:year |
1994
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pubmed:articleTitle |
A phase I study of intermittent infusion cladribine in patients with solid tumors.
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pubmed:affiliation |
Department of Medicine, University of Chicago Cancer Research Center, Illinois.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
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