Linked Life Data

7902302

Source:http://linkedlifedata.com/resource/pubmed/id/7902302

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1994-1-4
pubmed:abstractText
It has been demonstrated, that the H2-receptor antagonists: cimetidine and ranitidine-administered in doses of the same order of magnitude as reported for the inhibition of rat gastric secretion and development of the experimentally induced gastric and duodenal ulcer-are capable of increasing significantly the parotid secretion evoked by the cholinergic stimulant bethanechol. The salivary carbonic anhydrase activity was also elevated after combined treatment of bethanechol(+)-cimetidine. The similar action of the two H2-antagonists appears to suggest that their effect on salivation is connected probably with the cholinergic activity and it is concluded that the combination of bethanechol with these blockers may improve the esophageal clearance, an action that may be beneficial in the treatment of the gastroesophageal reflux disease.
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0015-5314
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[The effect of H2-receptor blockers (cimetidine and ranitidin) on parotid gland secretion and salivary carbonic anhydrase activity in the rat].
pubmed:affiliation
Semmelweis Orvostudományi Egyetem, Orálbiológiai Tanszék, Budapest.
pubmed:publicationType
Journal Article, English Abstract, Review