Linked Life Data

7901866

Source:http://linkedlifedata.com/resource/pubmed/id/7901866

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-12-22
pubmed:abstractText
Brain catecholamine and serotonin neurons are intimately involved in a number of physiological functions such as cardiovascular regulation, neuroendocrine secretion, regulation of behavior, mood and appetite control. The synthesis and release of these neurotransmitters appear to be remarkably correlated with the subsequent physiological changes observed. While there are numerous pharmacological approaches that affect the neurotransmitters involved (i.e., the catecholamines dopamine, noradrenaline and adrenaline as well as the indoleamine serotonin), one particularly attractive (while specific) approach involves the administration of a precursor amino acid. It is thus a prerequisite for the physiological and possibly therapeutic properties of the precursor amino acids l-tyrosine and l-tryptophan that they affect synthesis and release of their transmitter product. We will describe in detail the nature of the different neurochemical mechanisms guiding transmitter synthesis and their dependent physiological responses, in particular appetite control and neuroendocrine regulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0033-3190
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
18-32
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications.
pubmed:affiliation
III. Medizinische Klinik, Innere Medizin-Endokrinologie, Johannes-Gutenberg-Universitätsklinikum Mainz, BRD.
pubmed:publicationType
Journal Article, Review