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pubmed-article:7890250pubmed:abstractTextPrevious reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cervix. This suggests a local impairment of cell-mediated immunity by smoking. This immunosuppressive effect could support the concept that smoking is an independent risk factor for cervical neoplasia.lld:pubmed
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pubmed-article:7890250pubmed:articleTitleTobacco smoking impairs the local immunosurveillance in the uterine cervix. An immunohistochemical study.lld:pubmed
pubmed-article:7890250pubmed:affiliationDepartment of Obstetrics and Gynecology, KU Leuven, Belgium.lld:pubmed
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