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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-4-20
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pubmed:abstractText |
Previous reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cervix. This suggests a local impairment of cell-mediated immunity by smoking. This immunosuppressive effect could support the concept that smoking is an independent risk factor for cervical neoplasia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0378-7346
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7890250-Adult,
pubmed-meshheading:7890250-CD4-Positive T-Lymphocytes,
pubmed-meshheading:7890250-CD8-Positive T-Lymphocytes,
pubmed-meshheading:7890250-Case-Control Studies,
pubmed-meshheading:7890250-Cell Count,
pubmed-meshheading:7890250-Cervix Uteri,
pubmed-meshheading:7890250-Female,
pubmed-meshheading:7890250-HLA-DR Antigens,
pubmed-meshheading:7890250-Humans,
pubmed-meshheading:7890250-Immunologic Surveillance,
pubmed-meshheading:7890250-Langerhans Cells,
pubmed-meshheading:7890250-Middle Aged,
pubmed-meshheading:7890250-Smoking,
pubmed-meshheading:7890250-T-Lymphocyte Subsets
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pubmed:year |
1995
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pubmed:articleTitle |
Tobacco smoking impairs the local immunosurveillance in the uterine cervix. An immunohistochemical study.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, KU Leuven, Belgium.
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pubmed:publicationType |
Journal Article
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