Linked Life Data

7875544

Source:http://linkedlifedata.com/resource/pubmed/id/7875544

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-4-6
pubmed:abstractText
1. The alpha-1a adrenoceptor antagonist WB-4101, the alpha-1 adrenoceptor antagonist prazosin and the new activator of ATP-sensitive K+ channels HOE-234 were examined. The force of contraction and the rate of rise of contraction force were measured. 2. WB-4101 and HOE-234 were found to produce negative inotropic action in a dose dependent manner. This effect was attenuated by glibenclamide. On the other hand prazosin increased slightly the force of contraction and the rate of rise of contraction force in the same tissue. 3. The direct inotropic effects of above mentioned substances are compared and discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0306-3623
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1191-5
pubmed:dateRevised
2007-7-11
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Direct inotropic action of WB-4101 and prazosin in the guinea pig papillary muscle. Comparison with HOE-234, the new activator of ATP-sensitive K+ channels.
pubmed:affiliation
Department of Pharmacology, School of Medicine, Gda?sk, Poland.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro