Linked Life Data

7862609

Source:http://linkedlifedata.com/resource/pubmed/id/7862609

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1995-3-22
pubmed:abstractText
This study investigated the effects of heat stress and adrenocorticotropic hormone (ACTH) on the distribution of lymphocyte populations. Two experiments were conducted; each used 12-wk-old Cornell K-strain male chickens. In Experiment 1, birds were exposed to a temperature of 35 C, 6 h/d for 5 d and control birds were maintained at 24 C. In Experiment 2, birds received daily i.m. injections of 50 IU/kg body weight of ACTH for 5 d and control birds received .9% saline. On Day 6, blood and spleens were collected and lymphocytes were isolated. Indirect immunofluorescent labeling of lymphocytes were performed to detect B lymphocytes, CD4+ cells, and CD8+ cells. Neither ACTH injection nor heat stress affected percentages of B lymphocytes in the blood or the spleen. The CD4+ cells decreased significantly in the blood of ACTH-injected and heat-stressed birds and significantly increased in the spleens of heat-stressed birds. The CD4+ cells in the spleens of ACTH-injected birds did not differ from controls. The CD8+ cells significantly declined in the blood following both ACTH injection and heat stress and significantly increased in the spleen of the ACTH-injected birds but did not differ from controls in the heat-stressed birds. These results indicate that stress factors lead to redistribution of different lymphocyte populations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0032-5791
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1694-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The effects of adrenocorticotropic hormone and heat stress on the distribution of lymphocyte populations in immature male chickens.
pubmed:affiliation
Department of Poultry Science, Pennsylvania State University, University Park 16802.
pubmed:publicationType
Journal Article