|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1995-3-6
|
|
pubmed:abstractText |
A prior Phase II study of a 100-mg/m2 dose of docetaxel conducted at the Memorial Sloan-Kettering Cancer Center (New York, NY) demonstrated a 38% response rate with grade 3 or 4 neutropenia in 76% of the patients and a grade 2 or greater rash or infusion-related reaction in 41% and 34% of the patients, respectively. The current Phase II study sought to determine the activity of a 75-mg/m2 dose of docetaxel to establish whether this lower dose, combined with prednisone, ameliorates toxicity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0008-543X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
75
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
968-72
|
|
pubmed:dateRevised |
2010-3-24
|
|
pubmed:meshHeading |
pubmed-meshheading:7842417-Adult,
pubmed-meshheading:7842417-Aged,
pubmed-meshheading:7842417-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:7842417-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:7842417-Drug Therapy, Combination,
pubmed-meshheading:7842417-Female,
pubmed-meshheading:7842417-Humans,
pubmed-meshheading:7842417-Lung Neoplasms,
pubmed-meshheading:7842417-Male,
pubmed-meshheading:7842417-Middle Aged,
pubmed-meshheading:7842417-Neutropenia,
pubmed-meshheading:7842417-Paclitaxel,
pubmed-meshheading:7842417-Prednisone,
pubmed-meshheading:7842417-Premedication,
pubmed-meshheading:7842417-Survival Rate,
pubmed-meshheading:7842417-Taxoids
|
|
pubmed:year |
1995
|
|
pubmed:articleTitle |
Phase II trial of a 75-mg/m2 dose of docetaxel with prednisone premedication for patients with advanced non-small cell lung cancer.
|
|
pubmed:affiliation |
Department of Medicine, Memorial Sloan-Kettering Cancer Center, Cornell University Medical College, New York, New York 10021.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
|
