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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
46
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pubmed:dateCreated |
1995-2-27
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pubmed:abstractText |
Twenty-one patients fulfilling the Center for Disease Control criteria for chronic fatigue syndrome (CFS) were examined in a controlled study. Viral antibodies and tests evaluating the immune system were investigated in the patients and in a control group of 21 sex- and age-matched individuals. Production in vitro of the predominantly T-cell-derived cytokines interleukin-2 and interferon-gamma was significantly higher in patients with CFS compared the control group. Furthermore, the serum concentrations of IgA and IgE were significantly lower in patients with CFS; however, the values were within the normal reference range. All other variables were similar in the two groups. This study does not suggest a clearly disordered immune system or a chronic viral infection as a major pathogenetic factor in CFS. Longitudinal studies of immunological and virological parameters in CFS are warranted as are studies on patients that are severely handicapped.
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pubmed:commentsCorrections | |
pubmed:language |
dan
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0041-5782
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
156
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6836-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7839498-Adolescent,
pubmed-meshheading:7839498-Adult,
pubmed-meshheading:7839498-Aged,
pubmed-meshheading:7839498-Antibodies, Viral,
pubmed-meshheading:7839498-Autoantibodies,
pubmed-meshheading:7839498-Child,
pubmed-meshheading:7839498-Cross-Sectional Studies,
pubmed-meshheading:7839498-Denmark,
pubmed-meshheading:7839498-Fatigue Syndrome, Chronic,
pubmed-meshheading:7839498-Female,
pubmed-meshheading:7839498-Humans,
pubmed-meshheading:7839498-Immunoglobulins,
pubmed-meshheading:7839498-Male,
pubmed-meshheading:7839498-Middle Aged
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pubmed:year |
1994
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pubmed:articleTitle |
[Chronic fatigue syndrome--a controlled cross-sectional study].
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pubmed:affiliation |
Medicinsk afdeling TTA og infektionsmedicinsk afdeling M, Rigshospitalet, København.
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pubmed:publicationType |
Journal Article,
English Abstract
|