Linked Life Data

7809410

Source:http://linkedlifedata.com/resource/pubmed/id/7809410

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-1-27
pubmed:abstractText
The effective half-life (Teff) of radioactivity taken up by residual thyroid tumor after 131I therapy was measured and compared with response to treatment. Teff was determined from uptake by the lesions at four, eleven, and 18 days after 131I administration. The criterion for successful 131I therapy was that, in any successive 131I therapy, lesion uptake in the second therapy decreased to less than one-twentieth of that in the first therapy. In the 26 patients studied, 48 lesions were evaluated. Therapy was considered successful in 27 of these lesions and unsuccessful in 21. Mean Teff in the former was 2.48 +/- 0.93 days (mean +/- S.D.), significantly shorter than that in the latter, 5.70 +/- 2.62 days (p < 0.001). In some of the cases of solitary lesion, serum TSH levels, serum thyroglobulin values, and 131I protein bounded iodine (131I-PBI) were measured, but there were no significant differences between successful and unsuccessful therapy. The results of this study suggest that Teff seems to reflect the functional nature of the lesion and could be of prognostic value for the response to 131I therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0288-2043
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
167-70
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Iodine-131 treatment of thyroid cancer: relation between effective half-life and efficacy of treatment.
pubmed:affiliation
Department of Radiology, School of Medicine, Mie University, Japan.
pubmed:publicationType
Journal Article