Linked Life Data

779997

Source:http://linkedlifedata.com/resource/pubmed/id/779997

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-10-1
pubmed:abstractText
As a result of a WHO consultation in 1970 a guinea-pig antiserum, V801-501-058, was comprehensively evaluated by 11 collaborating laboratories in order to determine its usefulness as a reference reagent for the detection and assay of hepatitis B surface antigen (HB(s)Ag). The range of titres obtained were 1:64-1:256 by the immunodiffusion technique, 1:64-1:512 by counterimmunoelectrophoresis, 1:256-1:4096 by complement fixation, 1:6400-1:9600 by immune adherence haemagglutination, and <1:32 by platelet aggregation. The sensitivity of the guinea-pig antiserum for the detection of HB(s)Ag in serum and plasma samples was found to be equivalent to that of antisera obtained from other sources (man and baboon) with complement fixation and immune adherence haemagglutination, but it was slightly less sensitive with immunodiffusion and counterimmunoelectrophoresis. HB(s)Ag-positive reagent serum, which was used for the preparation of the immunogen, was found to have titres of 1:16-1:64 by immunodiffusion, 1:32-1:128 by counterimmunoelectrophoresis, 1:512-1:4096 by complement fixation, and 1:256-1:25 600 by immune adherence haemagglutination.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-92
pubmed:dateRevised
2010-10-26
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
WHO collaborative evaluation of reference hepatitis B surface antigen and antibody reagents, subtype ad.
pubmed:publicationType
Journal Article, Comparative Study