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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1995-7-27
|
| pubmed:abstractText |
In the Swiss Study "HIV and pregnancy" we observed 153 singleton pregnancies of HIV-positive women. 23 (15%) of those ended with a premature delivery. For drug addicts (n = 100), the incidence of prematurity, 20%, significantly higher than in those free of drugs (n = 53) with 5.6%. The most frequent cause of prematurity was premature labor or rupture of the membranes (n = 13), followed by maternal illness (n = 8) and fetal complications (n = 2). Women with premature delivery tended to have lower CD4 cell counts than those with term delivery (29.4% vs 12.0% with < 200 CD4 cells/microliters). Low CD4 cell counts and drug consumption are two independent but cumulative risks for severe infections. 16 of the 153 women (12 with, 4 without drug consumption) had severe infections during pregnancy; in 4 cases (25%), this led to prematurity. The most common infection was pneumonia (14/16), further one case of pyelonephritis and one of cerebral toxoplasmosis. Two of these 16 infants (12.5%) were HIV-positive. We could not confirm a relationship between prematurity and vertical HIV transmission. Of the HIV-classified children, 3/18 (16.7%) premature infants and 16/74 (21.6%) term infants were infected.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0948-2393
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
199
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
58-64
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:7788579-AIDS-Related Opportunistic Infections,
pubmed-meshheading:7788579-Adult,
pubmed-meshheading:7788579-CD4 Lymphocyte Count,
pubmed-meshheading:7788579-Cross-Sectional Studies,
pubmed-meshheading:7788579-Extraction, Obstetrical,
pubmed-meshheading:7788579-Female,
pubmed-meshheading:7788579-HIV Infections,
pubmed-meshheading:7788579-Humans,
pubmed-meshheading:7788579-Incidence,
pubmed-meshheading:7788579-Infant, Newborn,
pubmed-meshheading:7788579-Infectious Disease Transmission, Vertical,
pubmed-meshheading:7788579-Male,
pubmed-meshheading:7788579-Obstetric Labor, Premature,
pubmed-meshheading:7788579-Pilot Projects,
pubmed-meshheading:7788579-Pregnancy,
pubmed-meshheading:7788579-Pregnancy, High-Risk,
pubmed-meshheading:7788579-Pregnancy Complications, Infectious,
pubmed-meshheading:7788579-Substance Abuse, Intravenous,
pubmed-meshheading:7788579-Switzerland
|
| pubmed:articleTitle |
[Premature labor in HIV infected women. Swiss "HIV and Pregnancy" Study Group].
|
| pubmed:affiliation |
Klinik und Poliklinik für Geburtshilfe, Universitätsspital Zürich.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|