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pubmed-article:778346pubmed:abstractTextThis report describes the first fine structural locations of S-100 protein in the hamster cerebellum. Innovations in tissue fixation as well as tracer preparation enable localization of S-100 protein to several critical cellular and subcellular sites. Certain neuronal elements, Purkinje cells, contain S-100 protein in both cytoplasm and nucleus. Specific membrane structures including plasma membranes and the nuclear membranes of Purkinje cells are strikingly positive. Localization of S-100 protein to the pericapillary astrocytic endfeet as well as regions of the synapse are of particular biological interest. The clear nuclear localization of the molecule suggests a role in the genetic expression of the developing mammalian brain.lld:pubmed
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pubmed-article:778346pubmed:monthMaylld:pubmed
pubmed-article:778346pubmed:issn0022-510Xlld:pubmed
pubmed-article:778346pubmed:authorpubmed-author:NakaneP KPKlld:pubmed
pubmed-article:778346pubmed:authorpubmed-author:TabuchiKKlld:pubmed
pubmed-article:778346pubmed:authorpubmed-author:KirschW MWMlld:pubmed
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pubmed-article:778346pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:778346pubmed:year1976lld:pubmed
pubmed-article:778346pubmed:articleTitleThe fine structural localization of S-100 protein in rodent cerebellum.lld:pubmed
pubmed-article:778346pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:778346pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:778346pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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