Linked Life Data

7765740

Source:http://linkedlifedata.com/resource/pubmed/id/7765740

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-3-3
pubmed:abstractText
Mismatch-repair systems have been identified in organisms ranging from Escherichia coli to humans. They can repair almost all DNA base pair mismatches as well as small insertion/deletion mismatches. Molecular and biochemical analyses have shown that the core components of eukaryotic mismatch-repair systems are highly homologous to their bacterial counterparts. In humans, defects in four mismatch-repair genes have been linked both to hereditary non-polyposis colorectal cancer and to spontaneous cancers that exhibit rearrangements in DNA containing simple repeat sequences.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
B
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0958-1669
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:geneSymbol
HNPCC, MLH1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
585-94
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Mismatch repair and cancer susceptibility.
pubmed:affiliation
Dana Farber Cancer Institute, Boston.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review