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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1995-6-21
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pubmed:abstractText |
Galactose-specific lectin from Viscum album (VAA) was shown to induce the aggregation of rat thymocytes, to increase the intracellular Ca(2+)-availability, and to enhance the menadione-dependent release of H2O2 from cells in a carbohydrate- and dose-dependent manner. This activity was mediated by the carbohydrate-binding B-subunit, whereas the toxic A-subunit failed to display aggregating activity or to affect the intracellular Ca2+. However, incubation of cells in its presence decreased the release of H2O2. These data extend the knowledge of the immunomodulatory potency of VAA, especially its carbohydrate-binding B chain.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
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pubmed:issn |
0032-0943
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
130-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7753919-Animals,
pubmed-meshheading:7753919-Calcium,
pubmed-meshheading:7753919-Cell Aggregation,
pubmed-meshheading:7753919-Cells, Cultured,
pubmed-meshheading:7753919-Galactosides,
pubmed-meshheading:7753919-Lectins,
pubmed-meshheading:7753919-Male,
pubmed-meshheading:7753919-Mistletoe,
pubmed-meshheading:7753919-Plant Lectins,
pubmed-meshheading:7753919-Plants, Medicinal,
pubmed-meshheading:7753919-Rats,
pubmed-meshheading:7753919-Rats, Wistar,
pubmed-meshheading:7753919-Thymus Gland
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pubmed:year |
1995
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pubmed:articleTitle |
Influence of the galactoside-specific lectin from Viscum album and its subunits on cell aggregation and selected intracellular parameters of rat thymocytes.
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pubmed:affiliation |
Department of Biophysics, Belarusian State University, Minsk, Republic of Belarus.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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