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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1995-6-15
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pubmed:abstractText |
Activation in conscious dogs of the carotid chemoreflex or cardiac receptors results in coronary vasodilation that is mediated by a vagal cholinergic mechanism. Our previous study showed that the coronary vasodilation following activation of carotid chemoreflex is also mediated by nitric oxide (NO). In addition, NO production is depressed after the development of heart failure. Therefore, we hypothesized that the coronary vasodilation after activation of reflexes that elicit efferent vagal coronary vasodilation would be blunted in conscious dogs after pacing-induced heart failure due to the disappearance of NO.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2655-63
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7743629-Acetylcholine,
pubmed-meshheading:7743629-Adenosine,
pubmed-meshheading:7743629-Animals,
pubmed-meshheading:7743629-Arginine,
pubmed-meshheading:7743629-Cardiac Output, Low,
pubmed-meshheading:7743629-Cardiac Pacing, Artificial,
pubmed-meshheading:7743629-Chemoreceptor Cells,
pubmed-meshheading:7743629-Coronary Circulation,
pubmed-meshheading:7743629-Dogs,
pubmed-meshheading:7743629-Heart Rate,
pubmed-meshheading:7743629-Hemodynamics,
pubmed-meshheading:7743629-Nicotine,
pubmed-meshheading:7743629-Nitric Oxide,
pubmed-meshheading:7743629-Nitroarginine,
pubmed-meshheading:7743629-Reflex,
pubmed-meshheading:7743629-Vagus Nerve,
pubmed-meshheading:7743629-Vasodilation,
pubmed-meshheading:7743629-Veratrine
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pubmed:year |
1995
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pubmed:articleTitle |
Selective impairment of vagally mediated, nitric oxide-dependent coronary vasodilation in conscious dogs after pacing-induced heart failure.
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pubmed:affiliation |
Department of Physiology, New York Medical College, Valhalla 10595, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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