Linked Life Data

7737095

Source:http://linkedlifedata.com/resource/pubmed/id/7737095

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-6-8
pubmed:abstractText
Using a newly developed temperature-gradient gel electrophoresis apparatus, mutations in the K-ras oncogene and p53 tumor suppressor gene were analyzed for single-strand conformation polymorphism (SSCP). The mobilities of single-stranded DNAs, carrying various mutations, change--depending on the gel temperature during electrophoresis. Therefore, temperature-gradient single-strand conformation polymorphism (TG-SSCP) analysis can provide useful information concerning the optimum temperature for SSCP and may also be used to screen for various mutations or polymorphisms in a single electrophoretic run.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0173-0835
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:geneSymbol
c-Ki-ras2, p53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Single-strand conformation polymorphism analysis by perpendicular temperature-gradient gel electrophoresis.
pubmed:affiliation
Division of Clinical Laboratory, National Cancer Center Hospital.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't