Linked Life Data

7735939

Source:http://linkedlifedata.com/resource/pubmed/id/7735939

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1995-6-7
pubmed:abstractText
HYPOTHESIS: Long-term infection with Helicobacter pylori and the associated gastritis is now thought to cause a predisposition to gastric cancer through cellular changes resulting from inflammatory damage or because of direct effects of the bacterium. MICE AS MODELS FOR H. PYLORI-ASSOCIATED GASTRIC CANCER: Long-term infection of conventional Swiss mice with either H. felis or H. heilmannii results in atrophic gastritis. Infection of specific pathogen-free Balb/c mice results in the development of lesions similar to H. pylori-associated low-grade B-cell gastric lymphomas. CONCLUSION: H. pylori-infected mice appear to be excellent models for the study of tumours induced by this bacterium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0954-691X
pubmed:author
pubmed:issnType
Print
pubmed:volume
6 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S67-71
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The use of a mouse model in the study of Helicobacter sp.-associated gastric cancer.
pubmed:affiliation
School of Microbiology and Immunology, University of New South Wales, Sydney, Australia.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't