Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-6-1
pubmed:abstractText
Despite improved pretransfusion donor evaluation and testing, there is still residual risk of transfusion-associated viral infectious disease. Moreover, other important infectious pathogens, including bacteria, protozoa, and nonenveloped viruses, are not detected in current testing programs. Recent investigations from several laboratories have stimulated interest in decontamination of blood products as an additional means to further enhance the safety of blood transfusion. Furthermore, because testing is a retrospective strategy, a robust decontamination process could provide prospective protection against new pathogens that may enter the blood donor population. Recent advances in decontamination of fresh frozen plasma, plasma derivatives, platelet concentrates, and erythrocytes are reviewed. The introduction of solvent-detergent-treated plasma fractions marks an important advance in transfusion safety. Other technologies for cellular components are emerging to address transfusion-associated infectious disease transmission.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1040-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
42-6
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Advances in decontamination of blood components.
pubmed:affiliation
Department of Laboratory Medicine, University of California at San Francisco 94143-0100, USA.
pubmed:publicationType
Journal Article, Review