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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-5-18
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pubmed:abstractText |
Locust abdominal ganglia are shown to colocalize Locusta-diuretic peptide-, leucokinin I-, and lysine vasopressin-like immunoreactivity in posterior lateral neurosecretory cells. Extracts of abdominal ganglia were partially purified by RP-HPLC then dot immunoassay screened with the same antisera used for immunocytochemistry. Locusta-diuretic peptide-like immunoreactive material coeluted with synthetic Locusta-diuretic peptide, and leucokinin-like immunoreactive material coeluted with locustakinin. Lysine vasopressin-like material eluted in fractions that also showed Locusta-diuretic peptide and leucokinin I immunoreactivity. The diuretic activity of synthetic Locusta-diuretic peptide and locustakinin is demonstrated, and they are shown to act at least additively to promote Malpighian tubule fluid secretion. The immunoreactive neurosecretory cells are assumed to express at least these two peptides, and a model for promoting fluid secretion is proposed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0196-9781
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-104
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:7716080-Abdomen,
pubmed-meshheading:7716080-Amino Acid Sequence,
pubmed-meshheading:7716080-Animals,
pubmed-meshheading:7716080-Antigens,
pubmed-meshheading:7716080-Diuretics,
pubmed-meshheading:7716080-Female,
pubmed-meshheading:7716080-Ganglia, Invertebrate,
pubmed-meshheading:7716080-Grasshoppers,
pubmed-meshheading:7716080-Immunoassay,
pubmed-meshheading:7716080-Insect Hormones,
pubmed-meshheading:7716080-Lypressin,
pubmed-meshheading:7716080-Male,
pubmed-meshheading:7716080-Malpighian Tubules,
pubmed-meshheading:7716080-Molecular Sequence Data,
pubmed-meshheading:7716080-Neuropeptides,
pubmed-meshheading:7716080-Neurosecretory Systems,
pubmed-meshheading:7716080-Oligopeptides
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pubmed:year |
1995
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pubmed:articleTitle |
Cellular colocalization of diuretic peptides in locusts: a potent control mechanism.
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pubmed:affiliation |
Sussex Centre for Neuroscience, School of Biological Sciences, Brighton, UK.
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pubmed:publicationType |
Journal Article
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