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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1995-5-12
|
| pubmed:abstractText |
The Isle of Ely Diabetes Project is a prospective population-based study of the aetiology and pathogenesis of Type 2 diabetes mellitus. Between 1990 and 1992, 1156 subjects aged between 40 and 65 years underwent a standard 75 g oral glucose tolerance test (OGTT). A total of 1122 individuals who were not known to have diabetes completed the test and were classified according to WHO criteria; 51 subjects (4.5%) had previously undiagnosed diabetes and 188 (16.7%) had impaired glucose tolerance. The subjects with newly diagnosed glucose intolerance were significantly older, more obese, and shorter than those with normal glucose tolerance. Blood pressure, cholesterol, triglyceride, and LDL-cholesterol concentrations were elevated and HDL-cholesterol levels were lower among those with abnormal rather than normal glucose tolerance. In multiple regression analyses stratified by gender and including age, body mass index, and the waist-hip ratio as covariates, there were significant differences between those with normal and abnormal glucose intolerance in blood pressure, triglyceride, and HDL-cholesterol, but not total or LDL-cholesterol. In both male and female subjects, height had a significant independent negative association with the plasma glucose at 120 min after administration of oral glucose (standardized beta coefficient = -0.12, p < 0.01).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0742-3071
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
30-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7712700-Adult,
pubmed-meshheading:7712700-Aged,
pubmed-meshheading:7712700-Blood Pressure,
pubmed-meshheading:7712700-Body Height,
pubmed-meshheading:7712700-Body Mass Index,
pubmed-meshheading:7712700-Body Weight,
pubmed-meshheading:7712700-Cholesterol,
pubmed-meshheading:7712700-Cholesterol, HDL,
pubmed-meshheading:7712700-Cholesterol, LDL,
pubmed-meshheading:7712700-Diabetes Mellitus, Type 2,
pubmed-meshheading:7712700-England,
pubmed-meshheading:7712700-Female,
pubmed-meshheading:7712700-Glucose Intolerance,
pubmed-meshheading:7712700-Glucose Tolerance Test,
pubmed-meshheading:7712700-Humans,
pubmed-meshheading:7712700-Male,
pubmed-meshheading:7712700-Middle Aged,
pubmed-meshheading:7712700-Prospective Studies,
pubmed-meshheading:7712700-Sex Characteristics,
pubmed-meshheading:7712700-Triglycerides
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Undiagnosed glucose intolerance in the community: the Isle of Ely Diabetes Project.
|
| pubmed:affiliation |
Department of Community Medicine, University of Cambridge, UK.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|