Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-5-9
pubmed:abstractText
Herein we report the development of a canine model to examine transplacental and/or transmammary transmission of Neospora caninum. Six pregnant bitches were experimentally infected with N. caninum on day 21 of gestation. One bitch successfully delivered a litter of 3 live pups. These pups showed slight proprioception deficits, increased muscle tone, and spasticity in both pelvic limbs; however, N. caninum was neither demonstrated by bioassay in cell culture nor seen in histological sections of tissues from these pups. The remaining 5 bitches aborted. Neospora caninum was isolated from tissues of 4 of the experimentally infected bitches and pups from 2 of the miscarried litters. Experimental infections of 2 litters of 5-day-old nursing pups produced variable results. Neospora caninum was isolated from 2 of 2 inoculated pups in 1 litter and 3 of 6 inoculated pups in the second litter.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-3395
pubmed:author
pubmed:issnType
Print
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
208-11
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Vertical transmission of Neospora caninum in dogs.
pubmed:affiliation
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Alabama 36849, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't