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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-5-9
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pubmed:abstractText |
Herein we report the development of a canine model to examine transplacental and/or transmammary transmission of Neospora caninum. Six pregnant bitches were experimentally infected with N. caninum on day 21 of gestation. One bitch successfully delivered a litter of 3 live pups. These pups showed slight proprioception deficits, increased muscle tone, and spasticity in both pelvic limbs; however, N. caninum was neither demonstrated by bioassay in cell culture nor seen in histological sections of tissues from these pups. The remaining 5 bitches aborted. Neospora caninum was isolated from tissues of 4 of the experimentally infected bitches and pups from 2 of the miscarried litters. Experimental infections of 2 litters of 5-day-old nursing pups produced variable results. Neospora caninum was isolated from 2 of 2 inoculated pups in 1 litter and 3 of 6 inoculated pups in the second litter.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0022-3395
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
208-11
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7707195-Animals,
pubmed-meshheading:7707195-Animals, Newborn,
pubmed-meshheading:7707195-Antibodies, Protozoan,
pubmed-meshheading:7707195-Coccidiosis,
pubmed-meshheading:7707195-Disease Models, Animal,
pubmed-meshheading:7707195-Dogs,
pubmed-meshheading:7707195-Female,
pubmed-meshheading:7707195-Fetal Death,
pubmed-meshheading:7707195-Fetal Resorption,
pubmed-meshheading:7707195-Infectious Disease Transmission, Vertical,
pubmed-meshheading:7707195-Neospora,
pubmed-meshheading:7707195-Pregnancy,
pubmed-meshheading:7707195-Pregnancy Complications, Parasitic
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pubmed:year |
1995
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pubmed:articleTitle |
Vertical transmission of Neospora caninum in dogs.
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pubmed:affiliation |
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Alabama 36849, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|