Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-5-2
|
pubmed:abstractText |
Autoimmune hepatitis (AIH), an unresolving liver inflammation characterized by periportal hepatitis and presence of serum autoantibodies, is distinguished by smooth muscle antibody and/or antinuclear antibody seropositivity. Type-2 AIH is characterized by antibodies to liver/kidney microsome type-1. Antineutrophil cytoplasmic antibodies (ANCAs) are highly specific for ulcerative colitis, primary sclerosing cholangitis, and, in this report, type-1 AIH determined by positive enzyme-linked immunosorbent assay confirmed by perinuclear indirect immunofluorescence staining. The studies described characterize the frequency and nature of ANCA in severe type-1 AIH patients and define AIH-ANCA specificity and diagnostic significance.
|
pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0016-5085
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
108
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1159-66
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7698584-Adolescent,
pubmed-meshheading:7698584-Adult,
pubmed-meshheading:7698584-Aged,
pubmed-meshheading:7698584-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:7698584-Autoantibodies,
pubmed-meshheading:7698584-Autoimmune Diseases,
pubmed-meshheading:7698584-Biological Markers,
pubmed-meshheading:7698584-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7698584-Female,
pubmed-meshheading:7698584-Fluorescent Antibody Technique,
pubmed-meshheading:7698584-Hepatitis,
pubmed-meshheading:7698584-Humans,
pubmed-meshheading:7698584-Immunoglobulin G,
pubmed-meshheading:7698584-Male,
pubmed-meshheading:7698584-Middle Aged
|
pubmed:year |
1995
|
pubmed:articleTitle |
High-titer antineutrophil cytoplasmic antibodies in type-1 autoimmune hepatitis.
|
pubmed:affiliation |
Cedars-Sinai Inflammatory Bowel Disease Center, Cedars-Sinai Medical Center, Los Angeles, California.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|