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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1993-7-15
|
| pubmed:abstractText |
Some ventricular arrhythmias can be related to a decrease in the level of potassium (K) and/or magnesium (Mg). Because adrenergic stimulation decreases serum K+ and Mg++, we decided to investigate the effects of a beta-receptor agonist, isoproterenol, on serum K+ and Mg++, and their consequences on the induction of tachycardia. Programmed atrial and ventricular stimulation was performed in 95 patients before and during infusion of 1.6 micrograms.ml-1 of isoproterenol. During isoproterenol infusion, 61 patients had no inducible tachycardias (group I) and 34 had inducible sustained tachycardias (group II): 16 of them (group IIA) had inducible sustained supraventricular tachyarrhythmias and 18 (group IIB) had inducible sustained ventricular tachycardia. Serum K+ and Mg++ were measured at the end of stimulation in the control state and during isoproterenol infusion. The basal values in groups I and II did not differ (3.8 +/- 0.38 vs 3.86 +/- 0.39 mEq.l-1 for K+, and 20.18 +/- 2.68 vs 19.83 +/- 1.63 mg.l-1 for Mg++). Isoproterenol infusion induced a significant (P < 0.001) hypokalaemia in all groups and a decrease in serum Mg in group II: there was a significant decrease in serum Mg++ (P < 0.05) in group IIA (19.55 +/- 1.7 vs 20.4 +/- 4.6). The decrease in serum Mg++ in group IIB (18.9 +/- 1.55 vs 19.32 +/- 1.63) was not significant. However the serum Mg++ level during isoproterenol infusion was significantly lower in group IIB than in group I. In conclusion, the infusion of isoproterenol was responsible for a significant hypokalaemia, which did not explain the induction of tachycardia.(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0195-668X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
677-81
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:7685286-Adult,
pubmed-meshheading:7685286-Aged,
pubmed-meshheading:7685286-Cardiac Complexes, Premature,
pubmed-meshheading:7685286-Cardiac Pacing, Artificial,
pubmed-meshheading:7685286-Cardiomyopathy, Dilated,
pubmed-meshheading:7685286-Diagnosis, Differential,
pubmed-meshheading:7685286-Electrocardiography,
pubmed-meshheading:7685286-Female,
pubmed-meshheading:7685286-Humans,
pubmed-meshheading:7685286-Infusions, Intravenous,
pubmed-meshheading:7685286-Isoproterenol,
pubmed-meshheading:7685286-Magnesium,
pubmed-meshheading:7685286-Male,
pubmed-meshheading:7685286-Middle Aged,
pubmed-meshheading:7685286-Myocardial Infarction,
pubmed-meshheading:7685286-Potassium,
pubmed-meshheading:7685286-Syncope,
pubmed-meshheading:7685286-Tachycardia
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Effect of isoproterenol on serum potassium and magnesium.
|
| pubmed:affiliation |
Cardiology A-B, Chu de Brabois, Vandoeuvre, France.
|
| pubmed:publicationType |
Journal Article
|