rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1993-6-11
|
pubmed:abstractText |
Leukocyte adhesion involves at least three molecular families of adhesion proteins: the leukocyte integrins CD11/CD18, the intercellular adhesion molecules (ICAMs) and the carbohydrate-binding L-, E- and P-selectins. The intercellular adhesion molecules are well-known ligands for the CD11/CD18 integrins. We now show that E-selectin specifically binds to the sialyl Lex carbohydrate epitopes of leukocyte integrins. Thus, the different families of leukocyte adhesion molecules form an integrated adhesion network.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD11,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD18,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/E-Selectin,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Integrins,
http://linkedlifedata.com/resource/pubmed/chemical/Lewis Blood-Group System,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0959-6658
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
131-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7683936-Antigens, CD,
pubmed-meshheading:7683936-Antigens, CD11,
pubmed-meshheading:7683936-Antigens, CD18,
pubmed-meshheading:7683936-Cell Adhesion,
pubmed-meshheading:7683936-Cell Adhesion Molecules,
pubmed-meshheading:7683936-Cell Line,
pubmed-meshheading:7683936-E-Selectin,
pubmed-meshheading:7683936-Epitopes,
pubmed-meshheading:7683936-Integrins,
pubmed-meshheading:7683936-Leukocytes,
pubmed-meshheading:7683936-Lewis Blood-Group System,
pubmed-meshheading:7683936-Recombinant Proteins,
pubmed-meshheading:7683936-Transfection
|
pubmed:year |
1993
|
pubmed:articleTitle |
The vascular E-selectin binds to the leukocyte integrins CD11/CD18.
|
pubmed:affiliation |
Department of Biochemistry, University of Helsinki, Finland.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|