Linked Life Data

7676652

Source:http://linkedlifedata.com/resource/pubmed/id/7676652

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-10-13
pubmed:databankReference
pubmed:abstractText
A complete cDNA sequence is reported for LRV2-1, the first Leishmania RNA virus known to infect an Old World parasite, Leishmania major. Sequence analyses show that LRV2-1 differs significantly from members of the LRV1 genus which infect New World parasites. The data support a view that transmission of LRV is strictly vertical and suggest that LRV predate the divergence of Old and New World parasites. As a consequence of this divergence, conserved features can be identified for the first time in Leishmaniavirus proteins. A finding that the virus capsid and polymerase genes do not overlap is unique among the known Totiviridae and infers that a gag-pol fusion protein cannot be produced simply via tRNA slippage in LRV2-1.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0042-6822
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
212
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
84-90
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The complete sequence of Leishmania RNA virus LRV2-1, a virus of an Old World parasite strain.
pubmed:affiliation
Department of Microbiology & Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't