Linked Life Data

7673928

Source:http://linkedlifedata.com/resource/pubmed/id/7673928

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-10-18
pubmed:abstractText
The EtOAc extract of the whole plant of the Argentinian species Nierembergia aristata showed significant cytotoxicity against eleven different cancer cell lines. In addition to several known compounds, bioassay-guided fractionation led to the isolation of three new cardenolides, 17-epi-11 alpha-hydroxy-6, 7-dehydrostrophanthidin-3-O-beta-boivinopyranoside[1],6, 7-dehydrostrophanthidin-3-O-beta-boivinopyranoside [2], and 6,7-dehydrostrophanthidin-3-O-beta-oleandropyranoside[3], of which the latter demonstrated activity against all the cell lines tested. To our knowledge, this is the first report of the isolation of cardiac glycosides from a species in the Solanaceae.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
848-56
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Cardenolides from Nierembergia aristata.
pubmed:affiliation
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't