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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1995-10-17
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pubmed:abstractText |
Meningococcal disease (MCD) can present as meningitis, meningitis plus septicaemia or septicaemia alone. This 17-year retrospective study sought to determine if the proportion of cases presenting as septicaemia alone was increasing. Four hundred and forty-nine children with MCD were admitted between 1977 and 1993, 50 children died (11%). The proportion of cases with septicaemia alone increased from 7% in 1977-1985 to 36% in 1990-1993 (P < 0.0005). Mortality was highest in children with septicaemia alone (19%). Despite the increase in septicaemia, overall mortality did not alter over the 17 years. CONCLUSION: MCD should not be thought of as "meningitis", since 33% of cases now present as septicaemia alone. Nearly one in five children with septicaemia alone die. Information and publicity about MCD should focus on septicaemia, characterised by a petechial rash, as the life-threatening presentation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0340-6199
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
154
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
472-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7671946-Bacteremia,
pubmed-meshheading:7671946-Chi-Square Distribution,
pubmed-meshheading:7671946-England,
pubmed-meshheading:7671946-Humans,
pubmed-meshheading:7671946-Infant,
pubmed-meshheading:7671946-Meningitis, Meningococcal,
pubmed-meshheading:7671946-Meningococcal Infections,
pubmed-meshheading:7671946-Retrospective Studies,
pubmed-meshheading:7671946-Severity of Illness Index
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pubmed:year |
1995
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pubmed:articleTitle |
The changing presentations of meningococcal disease.
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pubmed:affiliation |
Institute of Child Health, Alder Hey Children's Hospital, Liverpool, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|