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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-10-6
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pubmed:abstractText |
Previous studies have shown that soft lenses dehydrate during lens wear. The purpose of this study was to determine the dehydration time course of 38% water content non-ionic Medalist, 58% ionic Acuvue and 74% non-ionic Permaflex lenses, and the relationship between dehydration and in vivo diameter, movement and symptoms of dryness. Nineteen subjects randomly wore three pairs of lenses, each for 7 h. Lens movement and diameter were measured in vivo and hydration after lens removal at 1, 3 and 7 h. Dryness was rated by the subjects using a visual analogue scale. A separate experiment was conducted to measure hydration changes after 7 continuous hours of lens wear. The water content of all three lens types decreased significantly over 7 h with Acuvue decreasing more than the Permaflex and Medalist lenses in the interrupted and continuous experiments (ANOVA P < 0.05). Dehydration of Acuvue was significantly greater in the 7 h continuous experiment (9.0 +/- 2.6% H2O, ANOVA P = 0.0062) compared to the interrupted experiment. Hydration levels measured for Acuvue lenses on subjects for control purposes at 0, 1, 3 and 7 h showed no difference over time (ANOVA P = 0.0711). Movement of Permaflex lenses decreased 0.60 +/- 0.57 mm (ANOVA P = 0.0005) over 7 h and the in vivo diameter of Acuvue lenses decreased by 0.12 +/- 0.16 mm (ANOVA P = 0.0569). Dryness ratings increased significantly and equally for all three lenses over 7 h (ANOVA P = 0.9833).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0275-5408
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
281-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7667020-Adult,
pubmed-meshheading:7667020-Contact Lenses, Hydrophilic,
pubmed-meshheading:7667020-Desiccation,
pubmed-meshheading:7667020-Female,
pubmed-meshheading:7667020-Humans,
pubmed-meshheading:7667020-Male,
pubmed-meshheading:7667020-Movement,
pubmed-meshheading:7667020-Time Factors,
pubmed-meshheading:7667020-Water,
pubmed-meshheading:7667020-Xerophthalmia
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pubmed:year |
1995
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pubmed:articleTitle |
Dehydration, lens movement and dryness ratings of hydrogel contact lenses.
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pubmed:affiliation |
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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