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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0006644,
umls-concept:C0006901,
umls-concept:C0037813,
umls-concept:C0039763,
umls-concept:C0039771,
umls-concept:C0086418,
umls-concept:C0205250,
umls-concept:C0302908,
umls-concept:C0332324,
umls-concept:C0439831,
umls-concept:C0567415,
umls-concept:C0680730,
umls-concept:C0809874,
umls-concept:C0812409,
umls-concept:C1148554
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pubmed:issue |
2
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pubmed:dateCreated |
1995-10-10
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pubmed:abstractText |
A sensitive and reliable analytical procedure has been established for the detection of theophylline (TH), theobromine (TB) and caffeine (CA) in human plasma and urine by gradient capillary high-performance liquid chromatography (HPLC)-frit-fast atom bombardment mass spectrometry (FAB-MS) (LC-frit-FAB-MS). Two capillary columns and a column-switching valve were used in this LC system to allow all of the sample injected to be introduced into the MS system. 7-Ethyltheophylline was used as the internal standard (I.S.). The xanthines in the specimen were extracted with an Extrelut column. The lowest detected amount was ca. 5 ng/ml using this method.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1572-6495
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
667
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:7663696-Caffeine,
pubmed-meshheading:7663696-Capillary Action,
pubmed-meshheading:7663696-Chromatography, High Pressure Liquid,
pubmed-meshheading:7663696-Humans,
pubmed-meshheading:7663696-Reproducibility of Results,
pubmed-meshheading:7663696-Sensitivity and Specificity,
pubmed-meshheading:7663696-Spectrometry, Mass, Fast Atom Bombardment,
pubmed-meshheading:7663696-Theobromine,
pubmed-meshheading:7663696-Theophylline
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pubmed:year |
1995
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pubmed:articleTitle |
Highly sensitive and rapid determination of theophylline, theobromine and caffeine in human plasma and urine by gradient capillary high-performance liquid chromatography-frit-fast atom bombardment mass spectrometry.
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pubmed:affiliation |
Department of Forensic Medicine, Fukuoka University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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