rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1995-3-9
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pubmed:abstractText |
Concentrations of interleukin (IL)-6, soluble IL-6 receptor (sIL-6R), and soluble tumor necrosis factor receptor (sTNFR) p55 and p75 were measured in 25 patients with sepsis syndrome. Sequential blood samples were drawn from patients during a 7-h period. IL-6 concentrations were 34-763,000 pg/mL; they were higher in nonsurvivors than survivors, but the difference was not statistically significant. In septic patients, the median sIL-6R concentration was significantly lower than in 19 healthy volunteers (43 vs. 80 ng/mL). sIL-6R concentrations in survivors were not significantly different than those in nonsurvivors. There was a negative correlation between IL-6 and sIL-6R in septic patients (r = -.72). In patients with moderately impaired renal function, sIL-6R levels were not affected, but the concentrations of sTNFRs were significantly higher.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor...
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0022-1899
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
171
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
469-72
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7661926-Adolescent,
pubmed-meshheading:7661926-Adult,
pubmed-meshheading:7661926-Aged,
pubmed-meshheading:7661926-Aged, 80 and over,
pubmed-meshheading:7661926-Antigens, CD,
pubmed-meshheading:7661926-Female,
pubmed-meshheading:7661926-Humans,
pubmed-meshheading:7661926-Interleukin-6,
pubmed-meshheading:7661926-Male,
pubmed-meshheading:7661926-Middle Aged,
pubmed-meshheading:7661926-Receptors, Interleukin,
pubmed-meshheading:7661926-Receptors, Interleukin-6,
pubmed-meshheading:7661926-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:7661926-Receptors, Tumor Necrosis Factor, Type I,
pubmed-meshheading:7661926-Receptors, Tumor Necrosis Factor, Type II,
pubmed-meshheading:7661926-Systemic Inflammatory Response Syndrome
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pubmed:year |
1995
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pubmed:articleTitle |
Circulating interleukin-6 receptor in patients with sepsis syndrome.
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pubmed:affiliation |
Department of Surgery, University Hospital Nijmegen, Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|