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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1995-9-27
|
| pubmed:abstractText |
Advances in basic immunology have markedly enhanced our understanding of immune-mediated renal disease, particularly in view of the growing recognition of the importance of T-cells in mediating renal injury. Recent milestones in investigative technology, including cell-culture techniques supporting T-cell clones and renal-derived cell populations, and genetic inbreeding of both recombinant and transgenic mice, provide a unique opportunity to study specific mechanisms of cell-mediated responses that target the kidney. In the past year the role of major histocompatibility complex molecule expression and T-cell repertoire selection has been better defined in some models of autoimmune renal disease. In addition, new observations regarding mechanisms that downregulate injurious T-cell-mediated responses may direct further studies that develop new therapeutic modalities.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
1062-4821
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
270-6
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading | |
| pubmed:year |
1995
|
| pubmed:articleTitle |
T-cell regulation of renal immune responses.
|
| pubmed:affiliation |
University of Pennsylvania Renal-Electrolyte, Philadelphia, USA.
|
| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|