Linked Life Data

7644429

Source:http://linkedlifedata.com/resource/pubmed/id/7644429

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-9-21
pubmed:abstractText
Two 21-d experiments were conducted to document the effects of an early immunologic stress and changes in dietary ME(n) on selected characteristics of immune function of newly hatched turkeys. Eight treatments were included in each experiment. Treatments were the result of complete factorial arrangements of two types of injection and four isonitrogenous diets. Turkeys in both experiments were injected i.p. with .5, .5, and .2 mL of saline (SAL) or .5, .5, and .2 mL of a solution of Escherichia coli lipopolysaccharide (LPS) (100 micrograms LPS/mL SAL) at 1, 3, and 5 d of age, respectively. In Experiment 1, two diets were formulated to contain 2,800 kcal ME(n)/kg. One was a corn-soybean meal based diet (CSBM) and the other contained 8% Solkafloc (SKF). A third diet (3,100 kcal ME(n)/kg) was formulated by substituting 8% sucrose (SUC) for the 8% SKF. The fourth diet (HE) included in Experiment 1 was formulated to contain 3,700 kcal ME(n)/kg. The CSBM and SUC diets and two additional diets were tested in Experiment 2. The latter were the CSBM diet containing 74.5 mg ibuprofen/kg (IBU) and a corn-soybean meal diet formulated to contain 3,100 kcal ME(n)/kg (CS31). Concentrations of plasma IgG and jejunal IgG and IgA were not affected by injection or diet. Age-related changes in Ig concentrations were consistently observed in Experiments 1 and 2. Injection with LPS reduced the number or responses of blood leukocytes to mitogens at 8 d of age (P < .01), as compared with samples from turkeys injected with SAL. Leukocytes in whole blood samples from turkeys fed the HE diet responded less to LPS stimulation than those fed the SUC diet (P < .01). Injection with LPS did not markedly affect the characteristics of immune function studied, and feeding a diet with 3,100 kcal ME(n)/kg and 28.5% crude protein did not measurably affect the characteristics of immune function of young turkeys.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0032-5791
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
998-1010
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effects of early immune stress and changes in dietary metabolizable energy on the development of newly hatched turkeys. 2. Selected characteristics of immune function.
pubmed:affiliation
Department of Animal Science, Iowa State University, Ames 50011, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't