| pubmed-article:7621816 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0027763 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0004927 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0039336 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
| pubmed-article:7621816 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:7621816 | pubmed:issue | 13 | lld:pubmed |
| pubmed-article:7621816 | pubmed:dateCreated | 1995-8-31 | lld:pubmed |
| pubmed-article:7621816 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7621816 | pubmed:abstractText | We report the sequence, expression pattern and mutant phenotype of malvolio (mvl), the Drosophila homologue of mammalian natural resistance-associated macrophage proteins (NRAMPs). In the mouse, this novel transporter is encoded by Bcg, a dominant gene that confers natural resistance to intracellular parasites. mvl was identified in a screen for mutants that affect taste behaviour. We show that loss-of-function as well as insertional mutants in mvl display defects in taste behaviour with no alterations in the physiology of the sensory neurons. Activity of the reporter enzyme beta-galactosidase, that reflects the expression pattern of mvl, is seen in mature sensory neurons and in macrophages. The conceptual translation of the mvl cDNA shows a striking similarity (65% identity) with human NRAMP with almost complete identity in a conserved consensus motif found in a number of ATP-coupled transporters. Based on its phenotype and expression pattern as well as its structural similarities to NRAMPs and a nitrate transporter in Aspergillus nidulans, we discuss a possible role for MVL in nitrite/nitrate transport and its implications. | lld:pubmed |
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| pubmed-article:7621816 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7621816 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7621816 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7621816 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7621816 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7621816 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:7621816 | pubmed:author | pubmed-author:RawII | lld:pubmed |
| pubmed-article:7621816 | pubmed:author | pubmed-author:ChiaWW | lld:pubmed |
| pubmed-article:7621816 | pubmed:author | pubmed-author:RodriguesVV | lld:pubmed |
| pubmed-article:7621816 | pubmed:author | pubmed-author:CheahP YPY | lld:pubmed |
