rdf:type |
|
lifeskim:mentions |
umls-concept:C0017547,
umls-concept:C0026832,
umls-concept:C0036849,
umls-concept:C0056248,
umls-concept:C0205372,
umls-concept:C0678594,
umls-concept:C0680022,
umls-concept:C1442518,
umls-concept:C1512665,
umls-concept:C1552652,
umls-concept:C1552685,
umls-concept:C1705195
|
pubmed:issue |
4
|
pubmed:dateCreated |
1995-8-24
|
pubmed:abstractText |
Titin is a gigantic protein located in the thick filament of vertebrate muscles. The putative functions of titin range from interactions with myosin and other muscle proteins to a role in muscle recoil. Analysis of its complete sequence has shown that titin is a multi-domain protein containing several copies of modules of 100 amino acids each. These are thought to belong to the fibronectin type-III and immunoglobulin superfamilies. So far, a complete structural determination has not been carried out on any of the titin modules.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0969-2126
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
391-401
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:7613868-Animals,
pubmed-meshheading:7613868-Chemistry, Physical,
pubmed-meshheading:7613868-Immunoglobulins,
pubmed-meshheading:7613868-Magnetic Resonance Spectroscopy,
pubmed-meshheading:7613868-Models, Molecular,
pubmed-meshheading:7613868-Muscle Proteins,
pubmed-meshheading:7613868-Myosin-Light-Chain Kinase,
pubmed-meshheading:7613868-Peptide Fragments,
pubmed-meshheading:7613868-Peptides,
pubmed-meshheading:7613868-Physicochemical Phenomena,
pubmed-meshheading:7613868-Protein Kinases,
pubmed-meshheading:7613868-Protein Structure, Secondary,
pubmed-meshheading:7613868-Protein Structure, Tertiary,
pubmed-meshheading:7613868-Sequence Alignment,
pubmed-meshheading:7613868-Sequence Homology, Amino Acid,
pubmed-meshheading:7613868-Surface Properties
|
pubmed:year |
1995
|
pubmed:articleTitle |
Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set.
|
pubmed:affiliation |
EMBL, Heidelberg, Federal Republic of Germany.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|