Linked Life Data

7587673

Source:http://linkedlifedata.com/resource/pubmed/id/7587673

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-12-6
pubmed:abstractText
30% third degree burn model of Wistar rat was used in this experiment. The animals were divided randomly into three groups (normal control, burn, and platelet-activating factor antagonist treatment). After poured E. coli which labelled with acridine orange into intestine, the rats were killed at 6, 12, 24, and 48 hrs postburn, the bacteria in mesentery lymph node (MLN), liver and pulmonary organisms were cultured and counted, also observed by fluorescent microscopy directly. The results showed that, in PAF antagonist (WEB2170) treatment group, the quantity of bacteria in MLN, liver and lung were decreased significantly (P < 0.001). The labelled bacteria in MLN, liver and lung of burn group were 100%, 80.0%, and 50.0% respectively compared with 40.0%, 30.0%, and 20.0% in treatment group. It is suggested that WEB 2170 could protect the intestine from bacteria translocation after burn injury.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0529-5815
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[The effect of platelet-activating factor antagonists on early bacteria translocation of rat after burn injury].
pubmed:affiliation
Institute of Burn Research, Southwest Hospital, Third Millitary Medical University, Chongqing.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't