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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
838
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pubmed:dateCreated |
1995-11-6
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pubmed:abstractText |
Eighty-nine consecutive patients attending for day-case colonoscopy were randomly allocated either polyethylene glycol/balanced electrolyte (PEG) mixture (n = 45) or a mannitol/Picolax mixture (n = 44). Both preparations were administered in two fractions. Patients recorded their experience of the preparation on a questionnaire and one of two experienced endoscopists (unaware of the type of preparation given) assessed the result of bowel cleansing. Carbon dioxide insufflation was used for all examinations. Good/excellent bowel cleansing occurred in significantly more patients given PEG, 43 (96%), than those allocated mannitol/Picolax, 34 (77%), p = 0.01. More patients receiving mannitol/Picolax were able to complete the preparation in full than patients receiving PEG (38 vs 27, p = 0.01). More patients found the taste of mannitol/Picolax pleasant compared to PEG (46% vs 20%). Both preparations had a similar side-effect profile. Of those patients tested, 13% receiving mannitol/Picolax had a postural drop in blood pressure and blood parameters suggestive of mild dehydration. A fractionated administration of PEG as a bowel preparation for day-case colonoscopy is well tolerated and superior as a cleansing agent to a mannitol/Picolax combination. Provided carbon dioxide is used as the insufflating agent, mannitol/Picolax is an acceptable alternative in fit, young patients intolerant of PEG.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-1420744,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-2070983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-2242740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-2693078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-3255917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-3678160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-3974464,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-499716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-6116073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-6706069,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-6714602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-6737332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-6786947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-7380204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7567754-913865
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0032-5473
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
476-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7567754-Administration, Oral,
pubmed-meshheading:7567754-Adult,
pubmed-meshheading:7567754-Aged,
pubmed-meshheading:7567754-Colonoscopy,
pubmed-meshheading:7567754-Day Care,
pubmed-meshheading:7567754-Drug Combinations,
pubmed-meshheading:7567754-Enema,
pubmed-meshheading:7567754-Humans,
pubmed-meshheading:7567754-Mannitol,
pubmed-meshheading:7567754-Middle Aged,
pubmed-meshheading:7567754-Picolines,
pubmed-meshheading:7567754-Polyethylene Glycols,
pubmed-meshheading:7567754-Taste,
pubmed-meshheading:7567754-Therapeutic Irrigation
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pubmed:year |
1995
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pubmed:articleTitle |
The quest for a more acceptable bowel preparation: comparison of a polyethylene glycol/electrolyte solution and a mannitol/Picolax mixture for colonoscopy.
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pubmed:affiliation |
Department of Endoscopy, St Mark's Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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